Red Sox rout Blue Jays in TorontoOrtiz hits two home runs to pass Yastrzemski for 36th on the all-time list
Ortiz matched Yastrzemski with a two-run blast to center off left-hander Brad Mills in the fourth, then broke the short-lived tie with another two-run shot off Mills in the fifth, his 21st and 22nd homers of the season.
It was the third multihomer game of the season for Ortiz and the 44th of his career.
Ortiz's first homer ended his 0-for-18 skid against Toronto and an 0-for-11 slump overall.
Mike Napoli followed Ortiz's second shot with his 12th homer, the fourth time this season Boston has gone back-to-back.
Stephen Drew added a three-run homer as the Red Sox connected a season-high four times and won for the eighth time in nine games.
Dustin Pedroia was the only Boston starter without a hit as the Red Sox set season highs in runs and hits (18). Pedroia went 0 for 4 before being replaced and is hitless in 13 at-bats.
John Lackey (11-6) allowed one run and two hits in seven innings to win his second straight start. Felix Doubront worked the eighth and Craig Breslow finished.
The Red Sox took the lead with two runs in the second and added four in the third, chasing Blue Jays right-hander Drew Hutchison. Boston blew it open with two more in the fourth and six in the fifth against Mills.
Hutchison (6-9) matched a career-high with six earned runs, the second straight outing he allowed that many, and gave up a career-high nine hits in 2 2-3 innings, his shortest non-injury start. Hutchison, who lost for the first time in three outings against Boston, fell to 2-5 with a 7.71 ERA in eight home starts.
Boston's Brock Holt made the defensive play of the game, leaping into the right field wall to retire Dan Johnson for the first out of the fifth.
NOTES: Ted Williams holds the Red Sox record with 521 home runs, followed by Yastrzemski (452) and then Ortiz (395). ... Red Sox OF Shane Victorino did not start. Victorino returned Saturday after being out since May 23 with an injured right hamstring. This was the first of seven straight games on turf for the Red Sox, who visit Tampa next. ... Toronto designated RHP Sergio Santos for assignment and recalled LHP Rob Rasmussen from Triple-A Buffalo. ... Boston 1B/C Ryan Lavarnway went 0 for 4 in the first game of his rehab assignment at Double-A Portland. Lavarnway has been out since May 30 with a fractured left hand. ... Cleveland Cavaliers F Tristan Thompson, who was born in suburban Toronto, threw out the first pitch. ... Boston RHP Jake Peavy (1-8) faces Toronto LHP J.A. Happ (7-5) on Tuesday.