Manning hurts ankle in first half against Redskins
Manning started his 150th consecutive game, but was injured throwing an incomplete pass under pressure from defensive end Chris Baker. He was intercepted by Josh Wilson on the next play and limped off the field, heading directly to the locker room.
Wilson was evaluated for a possible concussion at the end of the play, which set up a Washington field goal.
Washington defensive end Jarvis Jenkins also suffered a head injury in the first half.
Giants receiver Rueben Randle was knocked out of the game with a knee injury, while guard James Brewer and receiver Hakeem Nicks were questionable with ankle injuries.